Search on: RECEPTORS, TIE 
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Descriptor English:   Receptors, TIE 
Descriptor Spanish:   Receptores TIE 
Descriptor Portuguese:   Receptores de TIE 
Synonyms English:   TIE Receptor Tyrosine Kinases  
Tree Number:   D08.811.913.696.620.682.725.400.925
D12.776.543.750.060.687
Definition English:   A family of structurally-related tyrosine kinase receptors that are expressed predominantly in ENDOTHELIAL CELLS and are essential for development of BLOOD VESSELS (NEOVASCULARIZATION, PHYSIOLOGIC). The name derives from the fact that they are tyrosine kinases that contain Ig and EGF domains. 
Indexing Annotation English:   GEN; prefer specifics
History Note English:   2004; use RECEPTORS, TIE (NM) 1999-2003 
Allowable Qualifiers English:  
AD administration & dosage AG agonists
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CH chemistry CL classification
DF deficiency DE drug effects
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PH physiology
RE radiation effects TU therapeutic use
UL ultrastructure  
Record Number:   38227 
Unique Identifier:   D042764 

Occurrence in VHL:
 

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